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Autologous Fat Grafting as Primary Breast Reconstruction after Mastectomy Effects on Longitudinal BMI
Jennifer A. Hall BS, Eva Roy BS, Xiao Zhu MD, Francesco M. Egro MBChB, MSc, MRCS, Walter J. Joseph MD, Carolyn De La Cruz MD
University of Pittsburgh Medical Center
2020-02-10
Presenter: Jennifer Hall
Affidavit:
Dr. Nguyen
Director Name: Dr. Nguyen
Author Category: Medical Student
Presentation Category: Clinical
Abstract Category: Breast (Aesthetic and Recon.)
Background: Total autologous fat grafting can be used for post-mastectomy breast reconstruction. Weight gain in breast cancer patients is associated with a higher risk of recurrence, and currently no literature characterizes weight changes after total autologous fat grafting-based reconstruction.
Methods: Retrospective review of post-mastectomy autologous breast reconstruction from one surgeon from 2008-2017. 113 patients were included, twelve underwent total fat grafting. T-test analysis was performed to analyze changes in BMI.
Results: For autologous fat grafting-based reconstruction, the average percent change in BMI at 6 months,1 year, 2 years, 3 years, 4 years, 5 years, and 6 years was found to be 1.41%, -1.31%, -1.68%. -4.39%, -2.15%, -6.74%, and -10.82%. For autologous reconstruction, the average percent changes in BMI were found to be 0.20%, 1.30%, 1.61%, 2.53%, 3.89%, 3.92%, and 4.36%, respectively. There was not a significant correlation between changes in BMI and volume of fat injected or number of fat grafting procedures.
Conclusion: Both groups had similar initial changes in BMI, but the fat grafting group trended on weight loss and the autologous group trended on weight gain. The fat grafting group was associated with significant weight loss compared to the autologous group at 3 years (-4.39% vs 2.53%, p<0.05). Though potential weight gain should not be the primary factor in deciding reconstruction technique, this data demonstrate a possible long-term benefit of fat grafting on weight loss.
