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Exploring the Impact of HbA1c Levels and Diabetes Medications on Outcomes Following Panniculectomy

Jonathan Bernard, Patrick Kennedy, Paul Martinez, Ben Ormseth, Kevin Zhang, and Jeffrey Janis
The Ohio State University
2024-02-01

Presenter: Patrick Kennedy

Affidavit:
This work is the original work of The Ohio State University College of Medicine and the Department of Plastic and Reconstructive Surgery, comprised of the authors listed in the abstract. I support this submission.

Director Name: Gregory Pearson, MD

Author Category: Medical Student
Presentation Category: Clinical
Abstract Category: General Reconstruction

Background:
Patients undergoing panniculectomy operations often present with multiple comorbidities, thereby elevating their overall risk of complications. Research on pre-operative approaches to mitigate potential consequences of these comorbidities is essential, although there is little knowledge on the impact of HbA1c levels and diabetes medications on panniculectomy outcomes. This study aims to increase understanding of the impact of comorbidities on panniculectomy outcomes.

Methods:
This is a retrospective cohort study of patients undergoing panniculectomies at a single academic center from 8/9/2022 through 10/26/2023. Data collected included demographics, smoking status, comorbidities pre-operative glucose and HbA1c levels, previous surgical history, and surgical outcomes. Cohorts were divided according to history of post-operative complications and compared using descriptive and inferential statistics.

Results:
One hundred and eleven patients were included. Sixty-six patients reported never smoking (59.5%). Twenty-four patients had diabetes (21.6%). Thirty patients had HbA1c recorded pre-operatively with a mean of 5.55 � 0.53. Sixty-four patients (57.7%) had previous bariatric surgery, and 94 (84.7%) had other previous intra-abdominal surgeries. Forty-one patients (36.9%) had complications within six months. The complication cohort had significantly higher proportions of hypertension, COPD, and previous bariatric surgery (p-value <0.05).

Conclusion:
This study demonstrates that certain risk factors are associated with post-operative complications following panniculectomy. While HbA1c and pre-operative glucose measures were not significantly different between cohorts, other risk factors were. We believe an increased sample size with further data on anti-diabetic medications will elucidate their impact on post-operative outcomes.

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