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Patient Perception Of Postoperative Pain Following Administration Of Liposomal Bupivacaine In Plastic And Breast Surgery

Nathan Eberle MD, DDS Martin Newman, MD, FACS
Cleveland Clinic Florida
2014-02-26

Presenter: Nathan Eberle

Affidavit:
The material proposed for presentation in this abstract has not been published in any scientific journal or previously presented at a major meeting.The above material represents 80% of the original work of the resident.

Director Name: Martin Newman

Author Category: Resident Plastic Surgery
Presentation Category: Clinical
Abstract Category: Breast (Aesthetic and Recon.)

Background: Since obtaining FDA approval for postsurgical pain management in 2011, a number of well-designed studies have reported favorably on the safety and efficacy of liposomal bupivacaine (LB). However, the literature lacks adequate reports of patient perception of postoperative pain and subjective satisfaction.

Methods: A telephone survey of patients who received LB injection at time of operation at a single institution was contacted. Included were patients who underwent cosmetic, reconstructive and/or breast procedures. Patients were asked to report their perception of pain on POD# 1 and 3 using the verbal scale (1-10). Additionally, patients reported on: understanding of medications received; overall satisfaction; perception of economic value; and, perception of preference to elastomeric pump.

Results: A total of 50 patients met inclusion criteria and could be reached by telephone; 23(46%) cosmetic and 27(54%) reconstructive and/or breast procedures. Mean pain score reported 2.6[0-9] POD#1 and 3.6[0-8] POD#3.
24(48%) patients were aware they had received the medication. 49 (98%) reported they would want LB again if they needed surgery in the future and would pay $230 [$100-$1,000] for the medication. All (100%) patients favored LB over a perceived elastomeric pump device.

Conclusions: Patient perception of efficacy following the injection of LB correlates with previous clinical findings. Our experience with LB injections for cosmetic and reconstructive/breast procedures indicates that patients experienced low postoperative pain scores with high overall patient satisfaction. Additional studies comparing the use of LB to standard narcotic regimens and its use in multi-modality pain management are warranted.

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