<< Back to the abstract archive
Randomized Split Face Study of the Efficacy and Morbidity of Different Percentage Treatment With Fractional Photothermolysis
Matthew Brown, Samantha Zwiebel, David Rowe
University Hospitals Case Medical Center
2014-03-13
Presenter: Matthew Brown
Affidavit:
This study was performed primarily by the presenter and resident matthew brown.
Director Name: Hooman Soltanian
Author Category: Resident Plastic Surgery
Presentation Category: Clinical
Abstract Category: Aesthetics
Background: Studies involving fractional photothermolysis (FP) have used inconsistent treatment regimens with variable surface area percentages. There is no current literature to support which FP percentage area may serve a patient best from both morbidity and facial rejuvination outcomes.
Methods: 22 patients were enrolled in a randomized split face clinical trial where 10% surface area FP treatment was performed to one side of the face and 20% to the other side. Enrolled Patients and surgeons analyzing photographics were blinded to treatment side. Patient survey data was collected on their perceived pain, redness, and healing along with photographic documentation.
Results: 86% of patients noted an increased crusting and redness on the 20% treatment side at post procedure week 1(PPW1), although this decreased to 29% at PPW2. The mean difference in pain between sides was 0.14 and was non-significant (P=0.76). Photographic analysis using a 5 point likert scale yielded a mean increase in redness for the 20% side of 0.64 and 0.23 at 1 and 2 weeks post-procedure. Three month analysis yielded a mean improvement for small rhytids of 2.1 for the 10% side and 3.0 for 20% side (P =0.03). Improvement in pigmentary irregularity was 2.7 for 10% and 3.2 for 20%(P=0.4).
Conclusions:
A higher percentage area treatment may induce more redness and crusting without any increase in percieved pain. Preliminary results of long-term outcomes advocate that higher surface area treatment may yield increased improvement in fine facial rhytids. Pigmentary irregularites are equally improved by 10% or 20% FP treatment.
