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Epithelioid hemangioma (angiolymphoid hyperplagia with eosinophilia) of the scrotum treated with naproxen

Neilendu Kundu, Gaby Doumit
Cleveland clinic
2012-02-14

Presenter: Neilendu Kundu

Affidavit:
100 % of the above work represent the original work.

Director Name: Gaby Doumit

Author Category: Other Specialty Resident
Presentation Category: Clinical
Abstract Category: General Reconstruction

How does this presentation meet the established conference educational objectives?
The meetings objectives regarding knowledge of current concepts in plastic and reconstructive surgery – especially in difficult to treat disease processes – will be satisfied by this presentation. While epitheloid hemangioma of the scrotum is an extremely rare pathologic entity, we describe the treatment with non-steroidal anti-inflammatory medication is a novel approach to a process that has been treated by surgical excision in the past with high recurrence rates.

How will your presentation be used by practicing physicians in the audience?
Plastic surgeons are often called to assist in the treatment of difficult cutaneous pathology. This presentation will provide plastic surgeons in the audience a description of the aforementioned disease process as well as suspected pathophysiologic mechanisms, allowing them to have better outcomes and improved patient satisfaction when faced with these challenging patients.

Epitheloid hemangioma (angiolymphoid hyperplagia with eosinophilia) is a benign, dermal tumor of unknown etiology. While predominantly affecting the head and neck, fewer than 30 cases involving the scrotum have been published. Additional difficulty exists in determining therapy once the diagnosis is confirmed. As this represents an extremely rare entity, a multitude of anecdotal treatment modalities have been utilized including systemic/intralesional steroid therapy, radiotherapy, chemical therapy, etc. Surgical excision, however, remains the consensus treatment option, even with high recurrence rates. We present the case of a 14-year-old male with epitheloid hemangioma of the scrotum that had successful, regression using the non-steroidal anti-inflammatory Naprosyn (naproxen). To the best of our knowledge, this represents the first described treatment for scrotal epitheloid hemangioma using Naprosyn.

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