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Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma (PRP) for Treating Androgenic Alopecia
Bilsev Ince M.D., Mehmet Emin Cem Yildirim M.D., Mehmet Dadaci M.D., Mustafa Cihat Avunduk M.D., Nedim Savaci M.D.
Necmettin Erbakan University, Meram Faculty of Medicine Hospital, Department of Plastic Reconstructi
2018-02-14
Presenter: Mehmet Emin Cem Yildirim
Affidavit:
The presenter, who is Mehmet Emin Cem Yildirim M.D., has an active role in the study.
Director Name: Nedim Savaci
Author Category: Resident Plastic Surgery
Presentation Category: Clinical
Abstract Category: Aesthetics
PURPOSE
The aim of this study was to compare the increase in hair density, average number of platelets, complications, preparation, and duration of application in the treatment of AGA using activated autologous (a-PRP), nonactivated (n-PRP), and homologous PRP (h-PRP).
METHODS
We studied male patients who had experienced increased hair loss in the last year. Patients were divided into three groups: Group 1 received n-PRP, Group 2 received active PRP, and Group 3 received h-PRP. For Group 1, PRP was prepared by a single centrifugation prepared from the patient's own blood. For Group 2, the PRP was prepared from the patient's own blood, but a second centrifugation was applied for platelet activation with calcium chloride. For Group 3, the PRP was prepared from pooled platelets with the same blood group as the patient from the blood center. PRP was injected at 1, 2, and 6 months. The hair density (n/cm2) of each patient before and after injection was calculated.
RESULTS
At 2, 6, and 12 months after the first treatment, the increase in hair density was calculated as 11.2, 26.1, and 32.4%, respectively, in Group 1; 8.1, 12.5, and 20.8%, respectively, in Group 2; and 16.09, 36.41, and 41.76%, respectively, in Group 3.
CONCLUSION
The efficacy of both PRPs was determined in AGA treatment in our study. However, it was determined statistically that the increase in hair density with h-PRP was greater than with other groups. We believe that h-PRP therapy can be used in patients with AGA.
